The Thyolo district of Malawi is one of the districts in Malawi. The capital is Thyolo. The district covers an area of 1,715 km.² and has a population of 458,976. It is also has crossroads leading to Makwasa, Molere, Konzalendo, Thekerani onto Mouna and eventually Nsanje leading to another border with Mozambique.
Thyolo is located between Blantyre and Mulanje, perhaps the main tourist area here is the Satemwa Tea Estate. Satemwa lies, 1,462m, along the slope of Thyolo Mountain.